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Anti-ACSL5 Polyclonal Antibody (ARO-A11569)

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概述
货号ARO-A11569
品牌ProteoGenix
描述
Anti-ACSL5 Polyclonal Antibody (ARO-A11569) is a rabbit polyclonal antibody detecting Long-chain acyl-CoA synthetase 5, Long-chain-fatty-acid--CoA ligase 5, ACSL5, FACL5, LACS 5, Arachidonate--CoA ligase, ACS5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ACSL5 (Arg432-Asp683).
靶标Long-chain acyl-CoA synthetase 5, Long-chain-fatty-acid--CoA ligase 5, ACSL5, FACL5, LACS 5, Arachidonate--CoA ligase, ACS5
纯化方式Purified by antigen affinity column.
Accession号Q9ULC5
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Long-chain-fatty-acid--CoA ligase 5 (ACSL5) is a ~75 kDa protein. Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage. Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids. It was suggested that it may also stimulate fatty acid oxidation. At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL.

1. Gassler, N. et al. (2007) Gastroenterology 133, 587-98. PMID: 17681178
2. Nakahara, K. et al. (2012) Molecular cell 46, 461-71. PMID: 22633490
3. Ohkuni, A. et al. (2013) Biochemical and biophysical research communications 442, 195-201. PMID: 24269233
4. Al-Thihli, K. et al. (2021) Clinical genetics 99, 376-383. PMID: 33191500
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-ACSL5 Polyclonal Antibody

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