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Anti-PIDD1 Polyclonal Antibody (ARO-A11595)

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概述
货号ARO-A11595
品牌ProteoGenix
描述
Anti-PIDD1 Polyclonal Antibody (ARO-A11595) is a rabbit polyclonal antibody detecting Leucine-rich repeat and death domain-containing protein, PIDD1, p53-induced death domain-containing protein 1, PIDD, LRDD in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PIDD1 (Phe694-Arg885).
靶标Leucine-rich repeat and death domain-containing protein, PIDD1, p53-induced death domain-containing protein 1, PIDD, LRDD
纯化方式Purified by antigen affinity column.
Accession号Q9HB75
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

p53-induced death domain-containing protein 1 (PIDD1) is a ~99 kDa protein. Component of the DNA damage/stress response pathway that functions downstream of p53/TP53 and can either promote cell survival or apoptosis. Associated with CRADD and the CASP2 caspase, it forms the PIDDosome a complex that activates CASP2 and triggers apoptosis. Associated with IKBKG and RIPK1, it enhances sumoylation and ubiquitination of IKBKG which is important for activation of the transcription factor NF-kappa-B.

1. Lin, Y. et al. (2000) Nature genetics 26, 122-7. PMID: 10973264
2. Tinel, A. et al. (2004) Science (New York, N.Y.) 304, 843-6. PMID: 15073321
3. Janssens, S. et al. (2005) Cell 123, 1079-92. PMID: 16360037
4. Tinel, A. et al. (2007) The EMBO journal 26, 197-208. PMID: 17159900
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-PIDD1 Polyclonal Antibody

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