

| 货号 | ARO-A11646 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-FBLN5 Polyclonal Antibody (ARO-A11646) is a rabbit polyclonal antibody detecting UP50, Urine p50 protein, DANCE, Fibulin-5, Developmental arteries and neural crest EGF-like protein, Dance, FBLN5, FIBL-5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human FBLN5 (Leu99-Cys205). |
| 靶标 | UP50, Urine p50 protein, DANCE, Fibulin-5, Developmental arteries and neural crest EGF-like protein, Dance, FBLN5, FIBL-5 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9UBX5 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Fibulin-5 (FBLN5) is a ~50 kDa protein. Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. 1. Claus, S. et al. (2008) The Journal of investigative dermatology 128, 1442-50. PMID: 18185537 2. Nakamura, T. et al. (1999) The Journal of biological chemistry 274, 22476-83. PMID: 10428823 3. El-Hallous, E. et al. (2007) The Journal of biological chemistry 282, 8935-46. PMID: 17255108 |
| Note | For research use only. |

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