

| 货号 | ARO-A11739 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-HPV16 E7/Protein E7 Polyclonal Antibody (ARO-A11739) for research applications.
Highlights
|
| 种属反应性 | Human papillomavirus type 16 |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant HPV16 E7/Protein E7 (His2-Pro98). |
| 靶标 | Protein E7, E7 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P03129 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. |
| Note | For research use only. |

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