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Anti-TGFB1I1 Polyclonal Antibody (ARO-A11712)

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概述
货号ARO-A11712
品牌ProteoGenix
描述
Anti-TGFB1I1 Polyclonal Antibody (ARO-A11712) is a rabbit polyclonal antibody detecting Androgen receptor-associated protein of 55 kDa, Hydrogen peroxide-inducible clone 5 protein, Androgen receptor coactivator 55 kDa protein, ARA55, Hic-5, Transforming growth factor beta-1-induced transcript 1 protein, TGFB1I1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human TGFB1I1 (Phe252-Arg390).
靶标Androgen receptor-associated protein of 55 kDa, Hydrogen peroxide-inducible clone 5 protein, Androgen receptor coactivator 55 kDa protein, ARA55, Hic-5, Transforming growth factor beta-1-induced transcript 1 protein, TGFB1I1
纯化方式Purified by antigen affinity column.
Accession号O43294
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1) is a ~49 kDa protein. Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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