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Anti-SFN Polyclonal Antibody (ARO-A11695)

概述
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参考文献

概述

货号	ARO-A11695
品牌	ProteoGenix
描述	Anti-SFN Polyclonal Antibody (ARO-A11695) is a rabbit polyclonal antibody detecting Stratifin, Epithelial cell marker protein 1, HME1, 14-3-3 protein sigma, SFN in ELISA, IHC, WB. Suitable for Human, Mouse, Rat. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human SFN (Met1-Ser248).
靶标	Stratifin, Epithelial cell marker protein 1, HME1, 14-3-3 protein sigma, SFN
纯化方式	Purified by antigen affinity column.
Accession号	P31947
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	14-3-3 protein sigma (SFN) is a ~27 kDa protein. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention of GBP1 GTPase by binding to phosphorylated GBP1, thereby inhibiting the innate immune response. Also acts as a TP53/p53-regulated inhibitor of G2/M progression. 1. Wilker, EW. et al. (2005) The Journal of biological chemistry 280, 18891-8. PMID: 15731107 2. Rose, R. et al. (2012) Journal of structural biology 180, 65-72. PMID: 22634725 3. Stevers, LM. et al. (2017) The Biochemical journal 474, 1273-1287. PMID: 28202711 4. Fisch, D. et al. (2023) Science (New York, N.Y.) 382, eadg2253. PMID: 37797010 7. Rietscher, K. et al. (2018) Journal of cell science 131. PMID: 29678907
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-SFN Polyclonal Antibody

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