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Anti-Human PCBP2 Polyclonal Antibody (ARO-A11787)

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概述
货号ARO-A11787
品牌ProteoGenix
描述
Anti-Human PCBP2 Polyclonal Antibody (ARO-A11787) is a rabbit polyclonal antibody detecting Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PCBP2 (Asn11-Ser173).
靶标Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2
纯化方式Purified by antigen affinity column.
Accession号Q15366
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Poly(rC)-binding protein 2 (PCBP2) is a ~38 kDa protein. Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Also binds poly(rU). Acts as a negative regulator of antiviral signaling. Negatively regulates cellular antiviral responses mediated by MAVS signaling.

1. Walter, BL. et al. (2002) Journal of virology 76, 12008-22. PMID: 12414943
2. Leffers, H. et al. (1995) European journal of biochemistry 230, 447-53. PMID: 7607214
3. You, F. et al. (2009) Nature immunology 10, 1300-8. PMID: 19881509
4. Gu, H. et al. (2022) Nature communications 13, 1564. PMID: 35322803
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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