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Anti-Human RAB4A Polyclonal Antibody (ARO-A11798)

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概述
货号ARO-A11798
品牌ProteoGenix
描述
Anti-Human RAB4A Polyclonal Antibody (ARO-A11798) is a rabbit polyclonal antibody detecting Ras-related protein Rab-4A, RAB4A, RAB4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human RAB4A (Asp11-Gly181).
靶标Ras-related protein Rab-4A, RAB4A, RAB4
纯化方式Purified by antigen affinity column.
Accession号P20338
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Ras-related protein Rab-4A (RAB4A) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB4A is involved in protein transport. Also plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling.

1. Huber, SK. et al. (2005) FEBS letters 579, 2821-9. PMID: 15907487
2. Eathiraj, S. et al. (2005) Nature 436, 415-9. PMID: 16034420
3. Kofler, N. et al. (2018) The Journal of biological chemistry 293, 4805-4817. PMID: 29425100
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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