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Anti-Human ERLIN1 Polyclonal Antibody (ARO-A11828)

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概述
货号ARO-A11828
品牌ProteoGenix
描述
Anti-Human ERLIN1 Polyclonal Antibody (ARO-A11828) is a rabbit polyclonal antibody detecting SPFH1, SPFH domain-containing protein 1, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1, C10orf69, KEO4, Protein KE04, Endoplasmic reticulum lipid raft-associated protein 1, ERLIN1, Erlin-1, KE04 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human ERLIN1 (Glu29-Thr173).
靶标SPFH1, SPFH domain-containing protein 1, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1, C10orf69, KEO4, Protein KE04, Endoplasmic reticulum lipid raft-associated protein 1, ERLIN1, Erlin-1, KE04
纯化方式Purified by antigen affinity column.
Accession号O75477
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Erlin-1 (ERLIN1) is a ~39 kDa protein. Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.

1. Teo, QW. et al. (2023) Developmental cell 58, 2495-2509.e6. PMID: 37683630
2. Huber, MD. et al. (2013) The Journal of cell biology 203, 427-36. PMID: 24217618
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human ERLIN1 Polyclonal Antibody

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