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Anti-Human CHD1 Polyclonal Antibody (ARO-A11851)

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概述
货号ARO-A11851
品牌ProteoGenix
描述
Anti-Human CHD1 Polyclonal Antibody (ARO-A11851) is a rabbit polyclonal antibody detecting ATP-dependent helicase CHD1, CHD1, Chromodomain-helicase-DNA-binding protein 1, CHD-1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CHD1 (Ser1127-Thr1285).
靶标ATP-dependent helicase CHD1, CHD1, Chromodomain-helicase-DNA-binding protein 1, CHD-1
纯化方式Purified by antigen affinity column.
Accession号O14646
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ATP-dependent chromatin remodeler CHD1 is a ~196 kDa protein. ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome.

1. Sims, RJ. et al. (2007) Molecular cell 28, 665-76. PMID: 18042460
2. Pilarowski, GO. et al. (2018) Journal of medical genetics 55, 561-566. PMID: 28866611
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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