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Anti-Human WNT1 Polyclonal Antibody (ARO-A11820)

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概述
货号ARO-A11820
品牌ProteoGenix
描述
Anti-Human WNT1 Polyclonal Antibody (ARO-A11820) is a rabbit polyclonal antibody detecting WNT1, Proto-oncogene Wnt-1, INT1, Proto-oncogene Int-1 homolog in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human WNT1 (Gly32-Arg255).
靶标WNT1, Proto-oncogene Wnt-1, INT1, Proto-oncogene Int-1 homolog
纯化方式Purified by antigen affinity column.
Accession号P04628
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Proto-oncogene Wnt-1 (WNT1) is a ~40 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.

1. Keupp, K. et al. (2013) American journal of human genetics 92, 565-74. PMID: 23499309
2. Laine, CM. et al. (2013) The New England journal of medicine 368, 1809-16. PMID: 23656646
3. Mihara, E. et al. (2016) eLife 5. PMID: 26902720
4. Won, JY. et al. (2017) European journal of medical genetics 60, 411-415. PMID: 28528193
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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