

| 货号 | ARO-A11815 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human HORMAD1 Polyclonal Antibody (ARO-A11815) is a rabbit polyclonal antibody detecting Cancer/testis antigen 46, CT46, HORMA domain-containing protein 1, NOHMA, Newborn ovary HORMA protein, HORMAD1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human HORMAD1 (Ser21-Arg232). |
| 靶标 | Cancer/testis antigen 46, CT46, HORMA domain-containing protein 1, NOHMA, Newborn ovary HORMA protein, HORMAD1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q86X24 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | HORMA domain-containing protein 1 (HORMAD1) is a ~45 kDa protein. Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. |
| Note | For research use only. |

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