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Anti-Human UBXN1 Polyclonal Antibody (ARO-A11869)

概述
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参考文献

概述

货号	ARO-A11869
品牌	ProteoGenix
描述	Anti-Human UBXN1 Polyclonal Antibody (ARO-A11869) is a rabbit polyclonal antibody detecting UBX domain-containing protein 1, UBXN1, SAPK substrate protein 1, UBA/UBX 33.3 kDa protein, SAKS1 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human UBXN1 (Asp212-Ser297).
靶标	UBX domain-containing protein 1, UBXN1, SAPK substrate protein 1, UBA/UBX 33.3 kDa protein, SAKS1
纯化方式	Purified by antigen affinity column.
Accession号	Q04323
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	UBX domain-containing protein 1 (UBXN1) is a ~33 kDa protein. Ubiquitin-binding protein that plays a role in the modulation of innate immune response. Blocks both the RIG-I-like receptors (RLR) and NF-kappa-B pathways. Following viral infection, UBXN1 is induced and recruited to the RLR component MAVS. In turn, interferes with MAVS oligomerization, and disrupts the MAVS/TRAF3/TRAF6 signalosome. This function probably serves as a brake to prevent excessive RLR signaling. 1. Wang, P. et al. (2013) Cell reports 3, 1057-70. PMID: 23545497 2. Wang, YB. et al. (2015) The Journal of biological chemistry 290, 10395-405. PMID: 25681446 3. Hu, Y. et al. (2017) PLoS pathogens 13, e1006187. PMID: 28152074 4. Wu-Baer, F. et al. (2010) Molecular and cellular biology 30, 2787-98. PMID: 20351172
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human UBXN1 Polyclonal Antibody

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