

| 货号 | ARO-A11827 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human TBC1D23 Polyclonal Antibody (ARO-A11827) is a rabbit polyclonal antibody detecting NS4ATP1, TBC1D23, TBC1 domain family member 23, HCV non-structural protein 4A-transactivated protein 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human TBC1D23 (Gly15-Lys306). |
| 靶标 | NS4ATP1, TBC1D23, TBC1 domain family member 23, HCV non-structural protein 4A-transactivated protein 1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9NUY8 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | TBC1 domain family member 23 (TBC1D23) is a ~78 kDa protein. Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning. 1. Ivanova, EL. et al. (2017) American journal of human genetics 101, 428-440. PMID: 28823707 2. Shin, JJH. et al. (2017) Nature cell biology 19, 1424-1432. PMID: 29084197 3. Navarro Negredo, P. et al. (2018) Nature communications 9, 596. PMID: 29426865 |
| Note | For research use only. |

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