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Anti-Human SULT1C2 Polyclonal Antibody (ARO-A11852)

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概述
货号ARO-A11852
品牌ProteoGenix
描述
Anti-Human SULT1C2 Polyclonal Antibody (ARO-A11852) is a rabbit polyclonal antibody detecting SULT1C2, humSULTC2, Sulfotransferase 1C1, ST1C2, SULT1C#1, SULT1C1, Sulfotransferase 1C2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SULT1C2 (Lys12-Leu296).
靶标SULT1C2, humSULTC2, Sulfotransferase 1C1, ST1C2, SULT1C#1, SULT1C1, Sulfotransferase 1C2
纯化方式Purified by antigen affinity column.
Accession号O00338
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sulfotransferase 1C2 (SULT1C2) is a ~34 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the sulfate conjugation of phenolic compounds. Does not transfer sulfate to steroids, dopamine, acetaminophen, or alpha-naphthol. Except in mitochondria, where it can add sulfate to cholesterol producing cholesterol sulfate, which alters mitochondrial membrane organization, and impacts protein complex mobility increasing state-III respiration, thereby modulating mitochondrial respiration. Catalyzes the sulfation of the carcinogenic N-hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis.

1. Hehonah, N. et al. (1999) The international journal of biochemistry & cell biology 31, 869-82. PMID: 10481272
2. Freimuth, RR. et al. (2000) Genomics 65, 157-65. PMID: 10783263
3. Sakakibara, Y. et al. (1998) The Journal of biological chemistry 273, 33929-35. PMID: 9852044
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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