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Anti-Human STAC3 Polyclonal Antibody (ARO-A11837)

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概述
货号ARO-A11837
品牌ProteoGenix
描述
Anti-Human STAC3 Polyclonal Antibody (ARO-A11837) is a rabbit polyclonal antibody detecting SH3 and cysteine-rich domain-containing protein 3, STAC3 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human STAC3 (Ser249-Ile364).
靶标SH3 and cysteine-rich domain-containing protein 3, STAC3
纯化方式Purified by antigen affinity column.
Accession号Q96MF2
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

SH3 and cysteine-rich domain-containing protein 3 (STAC3) is a ~41 kDa protein. Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane.

1. Horstick, EJ. et al. (2013) Nature communications 4, 1952. PMID: 23736855
2. Wong King Yuen, SM. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E9520-E9528. PMID: 29078335
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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