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Anti-Human ATG2A Polyclonal Antibody (ARO-A11902)

概述
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参考文献

概述

货号	ARO-A11902
品牌	ProteoGenix
描述	Anti-Human ATG2A Polyclonal Antibody (ARO-A11902) is a rabbit polyclonal antibody detecting Autophagy-related protein 2 homolog A, ATG2A, KIAA0404 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human ATG2A (Arg233-Gly341).
靶标	Autophagy-related protein 2 homolog A, ATG2A, KIAA0404
纯化方式	Purified by antigen affinity column.
Accession号	Q2TAZ0
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Autophagy-related protein 2 homolog A (ATG2A) is a ~212 kDa protein. Lipid transfer protein involved in autophagosome assembly. Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. Binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to ATG9 (ATG9A or ATG9B) to the IM for membrane expansion. Lipid transfer activity is enhanced by WIPI1 and WDR45/WIPI4, which promote ATG2A-association with phosphatidylinositol 3-monophosphate (PI3P)-containing membranes. Also regulates lipid droplets morphology and distribution within the cell. 1. Bakula, D. et al. (2017) Nature communications 8, 15637. PMID: 28561066 2. Valverde, DP. et al. (2019) The Journal of cell biology 218, 1787-1798. PMID: 30952800 3. Maeda, S. et al. (2019) eLife 8. PMID: 31271352 4. Velikkakath, AK. et al. (2012) Molecular biology of the cell 23, 896-909. PMID: 22219374
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Human ATG2A Polyclonal Antibody

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