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Anti-Human DNAJA1 Polyclonal Antibody (ARO-A11895)

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概述
货号ARO-A11895
品牌ProteoGenix
描述
Anti-Human DNAJA1 Polyclonal Antibody (ARO-A11895) is a rabbit polyclonal antibody detecting DnaJ protein homolog 2, DNAJA1, Heat shock protein J2, HDJ2, HSJ-2, HSJ2, HSPF4, Heat shock 40 kDa protein 4, HSDJ, DNAJ2, DnaJ homolog subfamily A member 1, Human DnaJ protein 2, hDj-2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human DNAJA1 (Asn106-Asn327).
靶标DnaJ protein homolog 2, DNAJA1, Heat shock protein J2, HDJ2, HSJ-2, HSJ2, HSPF4, Heat shock 40 kDa protein 4, HSDJ, DNAJ2, DnaJ homolog subfamily A member 1, Human DnaJ protein 2, hDj-2
纯化方式Purified by antigen affinity column.
Accession号P31689
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

DnaJ homolog subfamily A member 1 (DNAJA1) is a ~44 kDa protein. Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as a co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV.

1. Terada, K. et al. (2000) The Journal of biological chemistry 275, 24728-34. PMID: 10816573
2. Rauch, JN. et al. (2014) The Journal of biological chemistry 289, 1402-14. PMID: 24318877
3. Gotoh, T. et al. (2004) Cell death and differentiation 11, 390-402. PMID: 14752510
4. Stark, JL. et al. (2014) Biochemistry 53, 1360-72. PMID: 24512202
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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