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Anti-Human BCCIP Polyclonal Antibody (ARO-A11903)

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概述
货号ARO-A11903
品牌ProteoGenix
描述
Anti-Human BCCIP Polyclonal Antibody (ARO-A11903) is a rabbit polyclonal antibody detecting Protein TOK-1, BRCA2 and CDKN1A-interacting protein, P21- and CDK-associated protein 1, BCCIP, TOK1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human BCCIP (Ser67-Val314).
靶标Protein TOK-1, BRCA2 and CDKN1A-interacting protein, P21- and CDK-associated protein 1, BCCIP, TOK1
纯化方式Purified by antigen affinity column.
Accession号Q9P287
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

BRCA2 and CDKN1A-interacting protein (BCCIP) is a ~35 kDa protein. During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole. Isoform 2/alpha is particularly important for the regulation of microtubule anchoring, microtubule stability, spindle architecture and spindle orientation, compared to isoform 1/beta. May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2.

1. Huhn, SC. et al. (2017) Oncogene 36, 4750-4766. PMID: 28394342
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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