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Anti-Human SNX1 Polyclonal Antibody (ARO-A12028)

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概述
货号ARO-A12028
品牌ProteoGenix
描述
Anti-Human SNX1 Polyclonal Antibody (ARO-A12028) is a rabbit polyclonal antibody detecting Sorting nexin-1, SNX1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SNX1 (Phe143-Ser522).
靶标Sorting nexin-1, SNX1
纯化方式Purified by antigen affinity column.
Accession号Q13596
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sorting nexin-1 (SNX1) is a ~59 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).

1. Cozier, GE. et al. (2002) The Journal of biological chemistry 277, 48730-6. PMID: 12198132
2. Bhatia, VK. et al. (2009) The EMBO journal 28, 3303-14. PMID: 19816406
3. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988
4. Carlton, J. et al. (2004) Current biology : CB 14, 1791-800. PMID: 15498486
5. Rojas, R. et al. (2007) Molecular and cellular biology 27, 1112-24. PMID: 17101778
6. Bujny, MV. et al. (2007) Journal of cell science 120, 2010-21. PMID: 17550970
7. Mari, M. et al. (2008) Traffic (Copenhagen, Denmark) 9, 380-93. PMID: 18088323
8. Kim, E. et al. (2010) Biochemical and biophysical research communications 403, 167-71. PMID: 21040701
9. Gullapalli, A. et al. (2006) Molecular biology of the cell 17, 1228-38. PMID: 16407403
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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