

| 货号 | ARO-A11969 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human PIH1D1 Polyclonal Antibody (ARO-A11969) is a rabbit polyclonal antibody detecting Nucleolar protein 17 homolog, PIH1D1, PIH1 domain-containing protein 1, NOP17 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human PIH1D1 (Glu15-Ser181). |
| 靶标 | Nucleolar protein 17 homolog, PIH1D1, PIH1 domain-containing protein 1, NOP17 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9NWS0 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | PIH1 domain-containing protein 1 (PIH1D1) is a ~32 kDa protein. Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex. 1. McKeegan, KS. et al. (2007) Molecular and cellular biology 27, 6782-93. PMID: 17636026 2. Zhai, N. et al. (2012) Journal of molecular cell biology 4, 231-41. PMID: 22368283 3. Kamano, Y. et al. (2013) FEBS letters 587, 3303-8. PMID: 24036451 4. Horejsí, Z. et al. (2010) Molecular cell 39, 839-50. PMID: 20864032 |
| Note | For research use only. |

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