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Anti-Human ACTR2 Polyclonal Antibody (ARO-A12020)

概述
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参考文献

概述

货号	ARO-A12020
品牌	ProteoGenix
描述	Anti-Human ACTR2 Polyclonal Antibody (ARO-A12020) is a rabbit polyclonal antibody detecting Actin-like protein 2, ARP2, Actin-related protein 2, ACTR2 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human ACTR2 (Met1-Arg394).
靶标	Actin-like protein 2, ARP2, Actin-related protein 2, ACTR2
纯化方式	Purified by antigen affinity column.
Accession号	P61160
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Actin-related protein 2 (ACTR2) is a ~44 kDa protein. ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. 1. Welch, MD. et al. (1997) Nature 385, 265-9. PMID: 9000076 2. Rao, J. et al. (2017) The Journal of clinical investigation 127, 4257-4269. PMID: 29058690 3. Yoo, Y. et al. (2007) The Journal of biological chemistry 282, 7616-23. PMID: 17220302 4. Schrank, BR. et al. (2018) Nature 559, 61-66. PMID: 29925947
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human ACTR2 Polyclonal Antibody

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