

| 货号 | ARO-A12036 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human UBE2K Polyclonal Antibody (ARO-A12036) is a rabbit polyclonal antibody detecting Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-protein ligase, UBE2K, HIP-2, E2 ubiquitin-conjugating enzyme K, Huntingtin-interacting protein 2, Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-conjugating enzyme E2 K, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, HIP2, LIG in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human UBE2K (Met1-Asn200). |
| 靶标 | Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-protein ligase, UBE2K, HIP-2, E2 ubiquitin-conjugating enzyme K, Huntingtin-interacting protein 2, Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-conjugating enzyme E2 K, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, HIP2, LIG |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P61086 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Ubiquitin-conjugating enzyme E2 K (UBE2K) is a ~22 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. |
| Note | For research use only. |

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