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Anti-Human SRP68 Polyclonal Antibody (ARO-A12029)

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概述
货号ARO-A12029
品牌ProteoGenix
描述
Anti-Human SRP68 Polyclonal Antibody (ARO-A12029) is a rabbit polyclonal antibody detecting Signal recognition particle 68 kDa protein, Signal recognition particle subunit SRP68, SRP68 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SRP68 (Met293-Gln540).
靶标Signal recognition particle 68 kDa protein, Signal recognition particle subunit SRP68, SRP68
纯化方式Purified by antigen affinity column.
Accession号Q9UHB9
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Signal recognition particle subunit SRP68 is a ~70 kDa protein. Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER. The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER. Binds the signal recognition particle RNA (7SL RNA), SRP72 binds to this complex subsequently. The SRP complex possibly participates in the elongation arrest function.

1. Lee, JH. et al. (2021) Science advances 7. PMID: 34020957
2. Iakhiaeva, E. et al. (2006) Protein science : a publication of the Protein Society 15, 1290-302. PMID: 16672232
3. Becker, MM. et al. (2017) Nucleic acids research 45, 470-481. PMID: 27899666
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human SRP68 Polyclonal Antibody

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