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Anti-Human DIABLO Polyclonal Antibody (ARO-A12011)

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概述
货号ARO-A12011
品牌ProteoGenix
描述
Anti-Human DIABLO Polyclonal Antibody (ARO-A12011) is a rabbit polyclonal antibody detecting Second mitochondria-derived activator of caspase, Diablo homolog, mitochondrial, DIABLO, Smac, SMAC, Direct IAP-binding protein with low pI in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human DIABLO (His66-Asp239).
靶标Second mitochondria-derived activator of caspase, Diablo homolog, mitochondrial, DIABLO, Smac, SMAC, Direct IAP-binding protein with low pI
纯化方式Purified by antigen affinity column.
Accession号Q9NR28
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Diablo IAP-binding mitochondrial protein is a ~27 kDa protein. Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/BRUCE by inhibiting its binding to caspases.

1. Bartke, T. et al. (2004) Molecular cell 14, 801-11. PMID: 15200957
2. Hunkeler, M. et al. (2023) Science (New York, N.Y.) 379, 1105-1111. PMID: 36758104
3. Ehrmann, JF. et al. (2023) Science (New York, N.Y.) 379, 1117-1123. PMID: 36758105
4. Dietz, L. et al. (2023) Science (New York, N.Y.) 379, 1112-1117. PMID: 36758106
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human DIABLO Polyclonal Antibody

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