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Anti-Human KIF2C Polyclonal Antibody (ARO-A12044)

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概述
货号ARO-A12044
品牌ProteoGenix
描述
Anti-Human KIF2C Polyclonal Antibody (ARO-A12044) is a rabbit polyclonal antibody detecting Mitotic centromere-associated kinesin, Kinesin-like protein 6, KIF2C, Kinesin-like protein KIF2C, KNSL6, MCAK in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human KIF2C (Asn229-Ser589).
靶标Mitotic centromere-associated kinesin, Kinesin-like protein 6, KIF2C, Kinesin-like protein KIF2C, KNSL6, MCAK
纯化方式Purified by antigen affinity column.
Accession号Q99661
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Kinesin-like protein KIF2C is a ~81 kDa protein. In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment.

1. Tanenbaum, ME. et al. (2011) Current biology : CB 21, 1356-65. PMID: 21820309
2. Bakhoum, SF. et al. (2009) Nature cell biology 11, 27-35. PMID: 19060894
3. Shrestha, RL. et al. (2013) Current biology : CB 23, 1514-26. PMID: 23891108
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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