

| 货号 | ARO-A12071 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human WDR18 Polyclonal Antibody (ARO-A12071) is a rabbit polyclonal antibody detecting WD repeat-containing protein 18, WDR18 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human WDR18 (Met1-Ala321). |
| 靶标 | WD repeat-containing protein 18, WDR18 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9BV38 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | WD repeat-containing protein 18 (WDR18) is a ~47 kDa protein. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. May play a role during development. 1. Fanis, P. et al. (2012) Molecular & cellular proteomics : MCP 11, 1263-73. PMID: 22872859 2. Finkbeiner, E. et al. (2011) The EMBO journal 30, 1067-78. PMID: 21326211 |
| Note | For research use only. |

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