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Anti-Human PPP1CC Polyclonal Antibody (ARO-A12074)

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概述
货号ARO-A12074
品牌ProteoGenix
描述
Anti-Human PPP1CC Polyclonal Antibody (ARO-A12074) is a rabbit polyclonal antibody detecting Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit, PPP1CC in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PPP1CC (Met1-Lys323).
靶标Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit, PPP1CC
纯化方式Purified by antigen affinity column.
Accession号P36873
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC) is a ~36 kDa protein. Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.

1. Djouder, N. et al. (2007) Molecular cell 28, 28-40. PMID: 17936702
2. Takagi, M. et al. (2014) The Journal of biological chemistry 289, 22877-22887. PMID: 25012651
3. Lee, JH. et al. (2010) The Journal of biological chemistry 285, 24466-76. PMID: 20516061
4. Schmutz, I. et al. (2011) PloS one 6, e21325. PMID: 21712997
5. Sivakumar, S. et al. (2017) Biology open 6, 1672-1679. PMID: 28982702
6. Nie, H. et al. (2013) Nature medicine 19, 322-8. PMID: 23396208
7. Wies, E. et al. (2013) Immunity 38, 437-49. PMID: 23499489
8. Liau, NPD. et al. (2022) Nature 609, 400-407. PMID: 35768504
9. Kwon, JJ. et al. (2022) Nature 609, 408-415. PMID: 35831509
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human PPP1CC Polyclonal Antibody

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