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Anti-Human SPRY4 Polyclonal Antibody (ARO-A12069)

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概述
货号ARO-A12069
品牌ProteoGenix
描述
Anti-Human SPRY4 Polyclonal Antibody (ARO-A12069) is a rabbit polyclonal antibody detecting Protein sprouty homolog 4, Spry-4, SPRY4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SPRY4 (Ser178-Arg270).
靶标Protein sprouty homolog 4, Spry-4, SPRY4
纯化方式Purified by antigen affinity column.
Accession号Q9C004
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein sprouty homolog 4 (SPRY4) is a ~32 kDa protein. Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. Represses integrin-mediated cell spreading via inhibition of TESK1-mediated phosphorylation of cofilin.

1. Leeksma, OC. et al. (2002) European journal of biochemistry 269, 2546-56. PMID: 12027893
2. Sasaki, A. et al. (2003) Nature cell biology 5, 427-32. PMID: 12717443
3. Tsumura, Y. et al. (2005) The Biochemical journal 387, 627-37. PMID: 15584898
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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