

| 货号 | ARO-A12094 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human MAGEC2 Polyclonal Antibody (ARO-A12094) is a rabbit polyclonal antibody detecting MAGEC2, MAGEE1, HCA587, Cancer/testis antigen 10, MAGE-C2 antigen, MAGE-E1 antigen, CT10, Melanoma-associated antigen C2, Hepatocellular carcinoma-associated antigen 587 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human MAGEC2 (Asp132-Ser328). |
| 靶标 | MAGEC2, MAGEE1, HCA587, Cancer/testis antigen 10, MAGE-C2 antigen, MAGE-E1 antigen, CT10, Melanoma-associated antigen C2, Hepatocellular carcinoma-associated antigen 587 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9UBF1 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Melanoma-associated antigen C2 (MAGEC2) is a ~41 kDa protein. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. |
| Note | For research use only. |

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