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Anti-Human RPA2 Polyclonal Antibody (ARO-A12122)

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概述
货号ARO-A12122
品牌ProteoGenix
描述
Anti-Human RPA2 Polyclonal Antibody (ARO-A12122) is a rabbit polyclonal antibody detecting RPA34, Replication protein A 34 kDa subunit, Replication protein A 32 kDa subunit, RF-A protein 2, RP-A p34, Replication factor A protein 2, REPA2, RPA2, RPA32, RP-A p32 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human RPA2 (Thr50-Glu270).
靶标RPA34, Replication protein A 34 kDa subunit, Replication protein A 32 kDa subunit, RF-A protein 2, RP-A p34, Replication factor A protein 2, REPA2, RPA2, RPA32, RP-A p32
纯化方式Purified by antigen affinity column.
Accession号P15927
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Replication protein A 32 kDa subunit (RPA2) is a ~29 kDa protein. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response.

1. Gupta, R. et al. (2007) Blood 110, 2390-8. PMID: 17596542
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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