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Anti-Human NSFL1C Polyclonal Antibody (ARO-A12136)

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概述
货号ARO-A12136
品牌ProteoGenix
描述
Anti-Human NSFL1C Polyclonal Antibody (ARO-A12136) is a rabbit polyclonal antibody detecting NSFL1 cofactor p47, p97 cofactor p47, NSFL1C, UBXN2C, UBX domain-containing protein 2C in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human NSFL1C (Ser271-Thr370).
靶标NSFL1 cofactor p47, p97 cofactor p47, NSFL1C, UBXN2C, UBX domain-containing protein 2C
纯化方式Purified by antigen affinity column.
Accession号Q9UNZ2
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

NSFL1 cofactor p47 (NSFL1C) is a ~40 kDa protein. Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase.

1. Soukenik, M. et al. (2004) FEBS letters 576, 358-62. PMID: 15498563
2. Kress, E. et al. (2013) The Journal of cell biology 201, 559-75. PMID: 23649807
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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