

| 货号 | ARO-A12256 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human RBM39 Polyclonal Antibody (ARO-A12256) is a rabbit polyclonal antibody detecting CAPER alpha, RNA-binding protein 39, RNA-binding region-containing protein 2, CAPERalpha, HCC1, RNPC2, RBM39, RNA-binding motif protein 39, Hepatocellular carcinoma protein 1, Splicing factor HCC1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human RBM39 (Thr146-Val326). |
| 靶标 | CAPER alpha, RNA-binding protein 39, RNA-binding region-containing protein 2, CAPERalpha, HCC1, RNPC2, RBM39, RNA-binding motif protein 39, Hepatocellular carcinoma protein 1, Splicing factor HCC1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q14498 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | RNA-binding protein 39 (RBM39) is a ~59 kDa protein. RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity. 1. Dowhan, DH. et al. (2005) Molecular cell 17, 429-39. PMID: 15694343 2. Loerch, S. et al. (2014) The Journal of biological chemistry 289, 17325-37. PMID: 24795046 3. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793 4. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394 5. Tari, M. et al. (2019) EMBO reports 20, e47604. PMID: 31271494 |
| Note | For research use only. |

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