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Anti-Human PTPN23 Polyclonal Antibody (ARO-A12258)

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概述
货号ARO-A12258
品牌ProteoGenix
描述
Anti-Human PTPN23 Polyclonal Antibody (ARO-A12258) is a rabbit polyclonal antibody detecting KIAA1471, PTPN23, PTP-TD14, His domain-containing protein tyrosine phosphatase, HD-PTP, Tyrosine-protein phosphatase non-receptor type 23, Protein tyrosine phosphatase TD14 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PTPN23 (Met1-His321).
靶标KIAA1471, PTPN23, PTP-TD14, His domain-containing protein tyrosine phosphatase, HD-PTP, Tyrosine-protein phosphatase non-receptor type 23, Protein tyrosine phosphatase TD14
纯化方式Purified by antigen affinity column.
Accession号Q9H3S7
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Tyrosine-protein phosphatase non-receptor type 23 (PTPN23) is a ~178 kDa protein. Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

1. Doyotte, A. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6308-13. PMID: 18434552
2. Stefani, F. et al. (2011) Current biology : CB 21, 1245-50. PMID: 21757351
3. Kim, J. et al. (2010) Nature 464, 1048-51. PMID: 20393563
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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