

| 货号 | ARO-A12279 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human GALE Polyclonal Antibody (ARO-A12279) is a rabbit polyclonal antibody detecting UDP-galactose 4-epimerase, UDP-N-acetylgalactosamine 4-epimerase, Galactowaldenase, UDP-glucose 4-epimerase, GALE, UDP-GalNAc 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human GALE (Met1-Ala348). |
| 靶标 | UDP-galactose 4-epimerase, UDP-N-acetylgalactosamine 4-epimerase, Galactowaldenase, UDP-glucose 4-epimerase, GALE, UDP-GalNAc 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q14376 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | UDP-glucose 4-epimerase (GALE) is a ~38 kDa protein. Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. |
| Note | For research use only. |

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