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Anti-Human GSDME Polyclonal Antibody (ARO-A12324)

概述
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参考文献

概述

货号	ARO-A12324
品牌	ProteoGenix
描述	Anti-Human GSDME Polyclonal Antibody (ARO-A12324) is a rabbit polyclonal antibody detecting ICERE-1, ICERE1, GSDME-CT, GSDME-NT, DFNA5, Inversely correlated with estrogen receptor expression 1, Gasdermin-E, GSDME, Non-syndromic hearing impairment protein 5 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
同种型	IgG
克隆类型	Polyclonal
免疫原	E. coli - derived recombinant Human GSDME (Met1-Cys235).
靶标	ICERE-1, ICERE1, GSDME-CT, GSDME-NT, DFNA5, Inversely correlated with estrogen receptor expression 1, Gasdermin-E, GSDME, Non-syndromic hearing impairment protein 5
纯化方式	Purified by antigen affinity column.
Accession号	O60443
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Gasdermin-E (GSDME) is a ~54 kDa protein. Precursor of a pore-forming protein that converts non-inflammatory apoptosis to pyroptosis. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-E, N-terminal) binds to membranes and forms pores, triggering pyroptosis. 1. Ding, J. et al. (2016) Nature 535, 111-6. PMID: 27281216 2. Wang, Y. et al. (2017) Nature 547, 99-103. PMID: 28459430 3. Zhou, B. et al. (2021) Cell reports 35, 108998. PMID: 33852854 4. Planès, R. et al. (2022) Molecular cell 82, 2385-2400.e9. PMID: 35594856 5. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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质量

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浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Human GSDME Polyclonal Antibody

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