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Anti-Human HERPUD1 Polyclonal Antibody (ARO-A12314)

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概述
货号ARO-A12314
品牌ProteoGenix
描述
Anti-Human HERPUD1 Polyclonal Antibody (ARO-A12314) is a rabbit polyclonal antibody detecting HERPUD1, HERP, Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, MIF1, KIAA0025, Methyl methanesulfonate (MMF)-inducible fragment protein 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human HERPUD1 (Glu8-Asn87).
靶标HERPUD1, HERP, Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, MIF1, KIAA0025, Methyl methanesulfonate (MMF)-inducible fragment protein 1
纯化方式Purified by antigen affinity column.
Accession号Q15011
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1) is a ~43 kDa protein. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway.

1. Schulze, A. et al. (2005) Journal of molecular biology 354, 1021-7. PMID: 16289116
2. Schulz, J. et al. (2017) Journal of cell science 130, 3322-3335. PMID: 28827405
3. Kim, TY. et al. (2008) Biochemical and biophysical research communications 369, 741-6. PMID: 18307982
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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