

| 货号 | ARO-A12291 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human CBX1 Polyclonal Antibody (ARO-A12291) is a rabbit polyclonal antibody detecting HP1Hsbeta, CBX, Chromobox protein homolog 1, Modifier 1 protein, Heterochromatin protein 1 homolog beta, HP1 beta, M31, CBX1, p25beta, Heterochromatin protein p25 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CBX1 (Glu24-Leu168). |
| 靶标 | HP1Hsbeta, CBX, Chromobox protein homolog 1, Modifier 1 protein, Heterochromatin protein 1 homolog beta, HP1 beta, M31, CBX1, p25beta, Heterochromatin protein p25 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P83916 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Chromobox protein homolog 1 (CBX1) is a ~21 kDa protein. Component of heterochromatin, which recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Also recognizes and binds histone H1.4 methylated at 'Lys-26' (H1.4K26me). Excluded from chromatin when histone H1.4 is Simultaneously methylated at Lys-26 (H1.4K26me) and phosphorylated at Ser-27 (H1.4S27Ph). Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. 1. Daujat, S. et al. (2005) The Journal of biological chemistry 280, 38090-5. PMID: 16127177 |
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理