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Anti-Human GNAT1 Polyclonal Antibody (ARO-A12276)

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概述
货号ARO-A12276
品牌ProteoGenix
描述
Anti-Human GNAT1 Polyclonal Antibody (ARO-A12276) is a rabbit polyclonal antibody detecting Transducin alpha-1 chain, GNATR, Guanine nucleotide-binding protein G(t) subunit alpha-1, GNAT1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human GNAT1 (Met1-Phe350).
靶标Transducin alpha-1 chain, GNATR, Guanine nucleotide-binding protein G(t) subunit alpha-1, GNAT1
纯化方式Purified by antigen affinity column.
Accession号P11488
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Guanine nucleotide-binding protein G(t) subunit alpha-1 (GNAT1) is a ~40 kDa protein. Functions as a signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina. Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding.

1. Naeem, MA. et al. (2012) Investigative ophthalmology & visual science 53, 1353-61. PMID: 22190596
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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