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Anti-Human POLI Polyclonal Antibody (ARO-A12304)

概述
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参考文献

概述

货号	ARO-A12304
品牌	ProteoGenix
描述	Anti-Human POLI Polyclonal Antibody (ARO-A12304) is a rabbit polyclonal antibody detecting RAD30 homolog B, RAD30B, DNA polymerase iota, Eta2, POLI in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human POLI (Arg53-Lys439).
靶标	RAD30 homolog B, RAD30B, DNA polymerase iota, Eta2, POLI
纯化方式	Purified by antigen affinity column.
Accession号	Q9UNA4
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	DNA polymerase iota (POLI) is a ~83 kDa protein. Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. 1. Tissier, A. et al. (2000) The EMBO journal 19, 5259-66. PMID: 11013228 2. Frank, EG. et al. (2001) The EMBO journal 20, 2914-22. PMID: 11387224 3. Haracska, L. et al. (2003) Genes & development 17, 2777-85. PMID: 14630940 4. Washington, MT. et al. (2004) Molecular and cellular biology 24, 5687-93. PMID: 15199127 5. Zhou, Y. et al. (2010) Nucleic acids research 38, 5036-46. PMID: 20388628 6. Nair, DT. et al. (2004) Nature 430, 377-80. PMID: 15254543
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human POLI Polyclonal Antibody

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