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Anti-Human RAB14 Polyclonal Antibody (ARO-A12384)

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概述
货号ARO-A12384
品牌ProteoGenix
描述
Anti-Human RAB14 Polyclonal Antibody (ARO-A12384) is a rabbit polyclonal antibody detecting RAB14, Ras-related protein Rab-14 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Chicken, Pongo abelii, Pig.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Chicken, Pongo abelii, Pig
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human RAB14 (Met1-Ser180).
靶标RAB14, Ras-related protein Rab-14
纯化方式Purified by antigen affinity column.
Accession号P61106
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Ras-related protein Rab-14 (RAB14) is a ~23 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB14 is involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes.

1. Linford, A. et al. (2012) Developmental cell 22, 952-66. PMID: 22595670
2. Yamamoto, H. et al. (2010) Molecular biology of the cell 21, 2746-55. PMID: 20534812
3. Lall, P. et al. (2015) The Journal of biological chemistry 290, 18817-32. PMID: 26032412
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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