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Anti-Human ARHGDIA Polyclonal Antibody (ARO-A12415)

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概述
货号ARO-A12415
品牌ProteoGenix
描述
Anti-Human ARHGDIA Polyclonal Antibody (ARO-A12415) is a rabbit polyclonal antibody detecting Rho GDP-dissociation inhibitor 1, GDIA1, Rho GDI 1, Rho-GDI alpha, ARHGDIA in ELISA, IHC, WB. Suitable for Bos taurus, Human, Macaca fascicularis, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Bos taurus, Human, Macaca fascicularis, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ARHGDIA (Asn69-Asp204).
靶标Rho GDP-dissociation inhibitor 1, GDIA1, Rho GDI 1, Rho-GDI alpha, ARHGDIA
纯化方式Purified by antigen affinity column.
Accession号P52565
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Rho GDP-dissociation inhibitor 1 (ARHGDIA) is a ~23 kDa protein. Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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