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Anti-Human VPS33B Polyclonal Antibody (ARO-A12410)

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概述
货号ARO-A12410
品牌ProteoGenix
描述
Anti-Human VPS33B Polyclonal Antibody (ARO-A12410) is a rabbit polyclonal antibody detecting Vacuolar protein sorting-associated protein 33B, hVPS33B, VPS33B in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human VPS33B (Met1-Ala617).
靶标Vacuolar protein sorting-associated protein 33B, hVPS33B, VPS33B
纯化方式Purified by antigen affinity column.
Accession号Q9H267
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Vacuolar protein sorting-associated protein 33B (VPS33B) is a ~70 kDa protein. May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Required for proper trafficking and targeting of the collagen-modifying enzyme lysyl hydroxylase 3 (LH3) to intracellular collagen. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity.

1. Gruber, R. et al. (2017) The Journal of investigative dermatology 137, 845-854. PMID: 28017832
2. Bach, H. et al. (2008) Cell host & microbe 3, 316-22. PMID: 18474358
3. Cullinane, AR. et al. (2010) Nature genetics 42, 303-12. PMID: 20190753
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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