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Anti-Human WDR1 Polyclonal Antibody (ARO-A12500)

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概述
货号ARO-A12500
品牌ProteoGenix
描述
Anti-Human WDR1 Polyclonal Antibody (ARO-A12500) is a rabbit polyclonal antibody detecting WD repeat-containing protein 1, Actin-interacting protein 1, WDR1, AIP1, NORI-1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Chicken.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus, Chicken
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human WDR1 (Met1-Tyr606).
靶标WD repeat-containing protein 1, Actin-interacting protein 1, WDR1, AIP1, NORI-1
纯化方式Purified by antigen affinity column.
Accession号O75083
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

WD repeat-containing protein 1 (WDR1) is a ~66 kDa protein. Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing. Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization.

1. Fujibuchi, T. et al. (2005) Biochemical and biophysical research communications 327, 268-75. PMID: 15629458
2. Kuhns, DB. et al. (2016) Blood 128, 2135-2143. PMID: 27557945
3. Pfajfer, L. et al. (2018) The Journal of allergy and clinical immunology 142, 1589-1604.e11. PMID: 29751004
4. Kato, A. et al. (2008) The Biochemical journal 414, 261-70. PMID: 18494608
5. Lechuga, S. et al. (2015) American journal of physiology. Gastrointestinal and liver physiology 308, G745-56. PMID: 25792565
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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