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Anti-Human RPS3 Polyclonal Antibody (ARO-A12471)

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概述
货号ARO-A12471
品牌ProteoGenix
描述
Anti-Human RPS3 Polyclonal Antibody (ARO-A12471) is a rabbit polyclonal antibody detecting Small ribosomal subunit protein uS3, RPS3, 40S ribosomal protein S3 in ELISA, IHC, WB. Suitable for Ambystoma mexicanum, Arabidopsis thaliana, Bos taurus, Dog, Drosophila melanogaster, Human, Ictalurus punctatus, Manduca sexta, Mouse, Oryctolagus cuniculus, Pongo abelii, Rat, Pig, Xenopus laevis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Ambystoma mexicanum, Arabidopsis thaliana, Bos taurus, Dog, Drosophila melanogaster, Human, Ictalurus punctatus, Manduca sexta, Mouse, Oryctolagus cuniculus, Pongo abelii, Rat, Pig, Xenopus laevis
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human RPS3 (Met1-Lys187).
靶标Small ribosomal subunit protein uS3, RPS3, 40S ribosomal protein S3
纯化方式Purified by antigen affinity column.
Accession号P23396
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Small ribosomal subunit protein uS3 (RPS3) is a ~26 kDa protein. Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS).

1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399
2. Vladimirov, SN. et al. (1996) European journal of biochemistry 239, 144-9. PMID: 8706699
3. Kim, J. et al. (1995) The Journal of biological chemistry 270, 13620-9. PMID: 7775413
4. Kim, SH. et al. (2005) Biochemical and biophysical research communications 328, 962-7. PMID: 15707971
5. Hegde, V. et al. (2004) DNA repair 3, 121-6. PMID: 14706345
6. Balyeva, KE. et al. (2008) Molekuliarnaia biologiia 42, 314-22. PMID: 18610840
7. Hegde, V. et al. (2004) Biochemistry 43, 14211-7. PMID: 15518571
8. Ko, SI. et al. (2008) Mutation research 648, 54-64. PMID: 18973764
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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