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Anti-Human PGRMC1 Polyclonal Antibody (ARO-A12460)

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概述
货号ARO-A12460
品牌ProteoGenix
描述
Anti-Human PGRMC1 Polyclonal Antibody (ARO-A12460) is a rabbit polyclonal antibody detecting PGRMC, mPR, IZA, Membrane-associated progesterone receptor component 1, HPR6.6, Dap1, PGRMC1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Pongo abelii, Pig.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus, Pongo abelii, Pig
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PGRMC1 (Pro75-Asp195).
靶标PGRMC, mPR, IZA, Membrane-associated progesterone receptor component 1, HPR6.6, Dap1, PGRMC1
纯化方式Purified by antigen affinity column.
Accession号O00264
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Membrane-associated progesterone receptor component 1 (PGRMC1) is a ~21 kDa protein. Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone.

1. Ryu, CS. et al. (2017) Frontiers in pharmacology 8, 159. PMID: 28396637
2. Kaluka, D. et al. (2015) Biochemistry 54, 1638-47. PMID: 25675345
3. Piel, RB. et al. (2016) Biochemistry 55, 5204-17. PMID: 27599036
4. Riad, A. et al. (2018) Scientific reports 8, 16845. PMID: 30443021
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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