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Anti-Human GDI2 Polyclonal Antibody (ARO-A12451)

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概述
货号ARO-A12451
品牌ProteoGenix
描述
Anti-Human GDI2 Polyclonal Antibody (ARO-A12451) is a rabbit polyclonal antibody detecting Guanosine diphosphate dissociation inhibitor 2, GDI-2, Rab GDP dissociation inhibitor beta, Rab GDI beta, RABGDIB, GDI2 in ELISA, IHC, WB. Suitable for Bos taurus, Dog, Human, Macaca fascicularis, Mouse, Pan troglodytes, Pongo abelii, Pongo pygmaeus, Rat, Pig.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Bos taurus, Dog, Human, Macaca fascicularis, Mouse, Pan troglodytes, Pongo abelii, Pongo pygmaeus, Rat, Pig
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human GDI2 (Met1-Asp445).
靶标Guanosine diphosphate dissociation inhibitor 2, GDI-2, Rab GDP dissociation inhibitor beta, Rab GDI beta, RABGDIB, GDI2
纯化方式Purified by antigen affinity column.
Accession号P50395
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Rab GDP dissociation inhibitor beta (GDI2) is a ~50 kDa protein. GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking. Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A.

1. Zhang, B. et al. (2015) PLoS biology 13, e1002129. PMID: 25860027
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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