注册
CN
首页 > 产品中心 > 抗体 > 一抗

Anti-Human SNX17 Polyclonal Antibody (ARO-A12444)

价格:
规格：
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

概述
货号ARO-A12444
品牌ProteoGenix
描述
Anti-Human SNX17 Polyclonal Antibody (ARO-A12444) is a rabbit polyclonal antibody detecting KIAA0064, SNX17, Sorting nexin-17 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SNX17 (Met1-Gly401).
靶标KIAA0064, SNX17, Sorting nexin-17
纯化方式Purified by antigen affinity column.
Accession号Q15036
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sorting nexin-17 (SNX17) is a ~52 kDa protein. Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).

1. Williams, R. et al. (2004) Molecular biology of the cell 15, 3095-105. PMID: 15121882
2. Knauth, P. et al. (2005) Journal of molecular biology 347, 813-25. PMID: 15769472
3. Singla, A. et al. (2024) Nature communications 15, 10193. PMID: 39587083
4. Ghai, R. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 7763-8. PMID: 21512128
5. Steinberg, F. et al. (2012) The Journal of cell biology 197, 219-30. PMID: 22492727
6. McNally, KE. et al. (2017) Nature cell biology 19, 1214-1225. PMID: 28892079
7. Czubayko, M. et al. (2006) Biochemical and biophysical research communications 345, 1264-72. PMID: 16712798
8. Donoso, M. et al. (2009) Molecular biology of the cell 20, 481-97. PMID: 19005208
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

Anti-Human SNX17 Polyclonal Antibody

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2