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Anti-Human ARHGEF25 Polyclonal Antibody (ARO-A12452)

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概述
货号ARO-A12452
品牌ProteoGenix
描述
Anti-Human ARHGEF25 Polyclonal Antibody (ARO-A12452) is a rabbit polyclonal antibody detecting Rho guanine nucleotide exchange factor 25, p63RhoGEF, GEFT, Guanine nucleotide exchange factor GEFT, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT, Rac/Cdc42/Rho exchange factor GEFT, ARHGEF25 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ARHGEF25 (Ser149-Ser490).
靶标Rho guanine nucleotide exchange factor 25, p63RhoGEF, GEFT, Guanine nucleotide exchange factor GEFT, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT, Rac/Cdc42/Rho exchange factor GEFT, ARHGEF25
纯化方式Purified by antigen affinity column.
Accession号Q86VW2
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Rho guanine nucleotide exchange factor 25 (ARHGEF25) is a ~63 kDa protein. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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