

| 货号 | ARO-A12498 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human CCT3 Polyclonal Antibody (ARO-A12498) is a rabbit polyclonal antibody detecting hTRiC5, CCT-gamma, T-complex protein 1 subunit gamma, TCP-1-gamma, CCTG, TRIC5, CCT3 in ELISA, IHC, WB. Suitable for Bos taurus, Human, Macaca fascicularis, Mouse, Pongo abelii, Rat, Pig, Xenopus laevis.
Highlights
|
| 种属反应性 | Bos taurus, Human, Macaca fascicularis, Mouse, Pongo abelii, Rat, Pig, Xenopus laevis |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human CCT3 (Lys15-Lys527). |
| 靶标 | hTRiC5, CCT-gamma, T-complex protein 1 subunit gamma, TCP-1-gamma, CCTG, TRIC5, CCT3 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P49368 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | T-complex protein 1 subunit gamma (CCT3) is a ~60 kDa protein. Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. 1. Freund, A. et al. (2014) Cell 159, 1389-403. PMID: 25467444 2. Gestaut, D. et al. (2022) Cell 185, 4770-4787.e20. PMID: 36493755 3. Kelly, JJ. et al. (2022) Nature structural & molecular biology 29, 420-429. PMID: 35449234 4. Liu, C. et al. (2023) Communications biology 6, 531. PMID: 37193829 5. Seo, S. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 1488-93. PMID: 20080638 |
| Note | For research use only. |

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